Here are the below SAP S/4 HANA post installation activities which need to be done after SAP S/4 HANA Installation. Perform below S4HANA 1809 post installation steps
  • Perform a full database backup
  • Perform the automated initial setup
  • Call Transaction STC01
  • Choose the task list SAP_BASIS_SETUP_INITIAL_CONFIG
  • Choose Execute
  • Install the SAPLICENSE for Application and HANA Database 
  • Configure the remote connection to SAP Support
  • Perform a consistency check – Run transaction SICK
  • Goto transaction DB13->Diagnostics->Missing tables and indexes
  • Configure Transport Management System (TMS)
  • Upload and set system profiles using transaction RZ10
  • Create logon and RFC server groups
  • Perform load configuration using SGEN – Generate all objects
  • Perform the client copy
  • Activate required Business functions 
  • SMTP Configuration 
  • Setup SAP Fiori 
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